Incidental Detection of Radiotracer Uptake in Spindle Cell Lipoma on 18F-PSMA PET/CT. (27th October 2022)

• Record Type: Journal Article
• Authors: Hod, Nir; Sherf, Yehonatan; Lantsberg, Sophie
• Is Part Of: Clinical nuclear medicine. Volume 47:Number 10(2022)
• Page Start: e663
• Page End: e665
• Publication Date: 2022-10-27
• Subjects: 18F-PSMA -- "false-positive" -- PET/CT -- soft tissue tumor -- spindle cell lipoma; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000004291
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract: An 84-year-old man underwent 18 F–prostate-specific membrane antigen (PSMA) PET/CT for staging of a newly diagnosed prostate adenocarcinoma. PET/CT revealed high 18 F-PSMA uptake in a thigh mass, which was initially suspected for a metastasis. Histopathology revealed a rare entity of spindle cell lipoma, which should be added to the reported list of neoplasms that can show "false-positive" PSMA uptake during evaluation of patients with prostate carcinoma representing a potential interpretative pitfall.