Rare case of uterine cervix lymphoma with spontaneous regression: Case report. Issue 2 (8th November 2020)

• Record Type: Journal Article
• Authors: Desana, Benedetta; Balbo Mussetto, Annalisa; Macera, Annalisa; Mariani, Luca; De Rosa, Giovanni; Cirillo, Stefano
• Is Part Of: Journal of obstetrics and gynaecology research. Volume 47:Issue 2(2021)
• Page Start: 807
• Page End: 811
• Publication Date: 2020-11-08
• Subjects: cervix lesion -- cervix lymphoma -- inconclusive biopsy -- pelvic magnetic resonance -- spontaneous regression; Gynecology -- Periodicals; Obstetrics -- Periodicals; 618.1005
• DOI: 10.1111/jog.14562
• Languages: English
• ISSNs: 1341-8076

Abstract

Abstract: Primary malignant lymphoma rarely occurs in the female reproductive tract, because of that they are often misdiagnosed. Lymphoma spontaneous regression is even rarer, but it is possible behavior of this disease. A case of 54‐year‐old female patient with a primary diffuse large B‐cell lymphoma of the cervix is presented. First assumption was sarcoma or atypical adenocarcinoma; biopsies have been inconclusive and, after a partial spontaneous regression, diagnosis of lymphoma was possible only after surgery. The diagnosis was a real challenge for clinicians, radiologists and pathologists for both localization and behavior. Difficulties in diagnosis led to an over‐treatment: a laparotomic bilateral hysteron salpingectomy with lymphadenectomy was performed, while chemotherapy alone would have been the right approach. Considering that prognosis and treatment of primary malignant lymphoma of the cervix are completely different than those of other malignant tumors of the uterus, this disease should be considered in the differential diagnosis.