Altered vitamin D metabolic system in follicular cysts of sows. Issue 1 (3rd December 2020)

• Record Type: Journal Article
• Authors: Grzesiak, Malgorzata; Socha, Magdalena; Hrabia, Anna
• Is Part Of: Reproduction in domestic animals. Volume 56:Issue 1(2021)
• Page Start: 193
• Page End: 196
• Publication Date: 2020-12-03
• Subjects: CYP24A1 -- CYP27B1 -- ovarian cysts -- pig -- vitamin D; Animal breeding -- Periodicals; Veterinary pathology -- Periodicals; Livestock -- Breeding -- Periodicals; 636.082
• DOI: 10.1111/rda.13867
• Languages: English
• ISSNs: 0936-6768

Abstract

Contents: This study aimed to examine 25OHD3 concentration in the fluid of follicular and follicular lutein cysts of sows in comparison with preovulatory follicles as well as immunolocalize vitamin D metabolic enzymes (CYP27B1 and CYP24A1) and determine their protein abundances in the cyst wall. We have shown for the first time that 25OHD3 level in the fluid of both cyst types was significantly lower than in preovulatory follicles. Furthermore, we have demonstrated CYP27B1 and CYP24A1 protein immunolocalization and abundance in follicular and follicular lutein cysts. The abundance of protein for both metabolic enzymes was decreased in ovarian cysts when compared to preovulatory follicles. We propose that altered VD metabolism in ovarian cyst might associate with their formation in sows.