Epidemiology, clinical, and laboratory profile of patients with hepatitis C: A prospective, observational study from north-eastern India. (October 2022)

• Record Type: Journal Article
• Authors: Barman, Bhupen; Roy, Akash; Nune, Arvind; Lyngdoh, W. Valarie; Jamil, Md; Tiewsoh, Iadarilang
• Is Part Of: Tropical doctor. Volume 52:Number 4(2022)
• Page Start: 484
• Page End: 488
• Publication Date: 2022-10
• Subjects: hepatitis -- Asia -- diagnosis -- public health; Tropical medicine -- Periodicals; Medical care -- Developing countries -- Periodicals; Developing Countries -- Periodicals; Tropical Medicine -- Periodicals; Tropische geneeskunde; 616.9883
• DOI: 10.1177/00494755221110636
• Languages: English
• ISSNs: 0049-4755

Abstract

Low and middle-income countries (LMICs) contribute to 80% of the global hepatitis C virus (HCV) infection burden. Intravenous drug use (IVDU) is not uncommon in Northeastern India, thus contributing to HCV. Its epidemiology, clinical, and laboratory profile were studied in a tertiary care centre in northeastern India.HCV patients (age >18) of either sex were prospectively assessed for demographic, virological, and genotype distributions. Most were male (M: F, 5.8:1) with a mean age of 37.1 ± 11.8 years. The most common risk factor was IVDU(77.69%), followed by concomitant alcohol use in 69.2%. Besides genotype 3 (59.2%), genotype 1 (26.1%) and genotype 6 were also common (14.6%). The demographics, liver disease severity, and biochemical parameters were similar across genotypes.