Prevalence and clinical implications of persistent or exertional cardiopulmonary symptoms following SARS-CoV-2 infection in 3597 collegiate athletes: a study from the Outcomes Registry for Cardiac Conditions in Athletes (ORCCA). Issue 16 (1st November 2021)

• Record Type: Journal Article
• Authors: Petek, Bradley J; Moulson, Nathaniel; Baggish, Aaron L; Kliethermes, Stephanie A; Patel, Manesh R; Churchill, Timothy W; Harmon, Kimberly G; Drezner, Jonathan A
• Other Names: author non-byline.; Asif Irfan M author non-byline.; Baggish Aaron L author non-byline.; Borchers James author non-byline.; Drezner Jonathan A author non-byline.; Edenfield Katherine M author non-byline.; Emery Michael S author non-byline.; Goerl Kyle author non-byline.; Hainline Brian author non-byline.; Harmon Kimberly G author non-byline.; Jone Pei-Ni author non-byline.; Kim Jonathan H author non-byline.; Kliethermes Stephanie author non-byline.; Kraus William E author non-byline.; Lampert Rachel author non-byline.; Leiszler Matthew author non-byline.; Levine Benjamin D author non-byline.; Martinez Matthew W author non-byline.; Moulson Nathaniel author non-byline.; GO'Connor Francis author non-byline.; Patel Manesh R author non-byline.; Petek Bradley J author non-byline.; Phelan Dermot author non-byline.; Rink Lawrence D author non-byline.; Taylor Herman A author non-byline.; Ade Carl author non-byline.; Aiyer Aryan author non-byline.; Alfadhli Jarrah author non-byline.; Amaradio Chloe author non-byline.; Anderson Scott author non-byline.; Arlis-Mayor Stephanie author non-byline.; Aubry Jonathan S author non-byline.; Austin Andrea author non-byline.; Balcik Brenden J author non-byline.; Beaver Timothy author non-byline.; Benitez Nicolas author non-byline.; Berkstresser Brant author non-byline.; Best Thomas M author non-byline.; Bohon Tiffany author non-byline.; Bonnet Jonathan P author non-byline.; Boyington Elizabeth author non-byline.; Bray James author non-byline.; Bryant Jenna author non-byline.; Carnahan Sean author non-byline.; Chamberlain Rachel author non-byline.; Charters Samantha author non-byline.; Chill Nicholas author non-byline.; Clark Daniel E author non-byline.; Comeau Douglas author non-byline.; Cook Laura E author non-byline.; Corey Deanna author non-byline.; Costa Amy author non-byline.; Crowther Marshall author non-byline.; Dalia Tarun author non-byline.; Davidson Craig author non-byline.; Davitt Kaitlin author non-byline.; Maurice Annabelle DeSt author non-byline.; Dean Peter N author non-byline.; Dendy Jeffrey M author non-byline.; DeZenzo Katelyn author non-byline.; Dimitris Courtney author non-byline.; Doperak Jeanne author non-byline.; Duffaut Calvin author non-byline.; Fafara Craig author non-byline.; Fahy Katherine author non-byline.; Ferderber Jason author non-byline.; Finn Megan author non-byline.; Fish Frank A author non-byline.; Warne Fitch R author non-byline.; Galante Angelo author non-byline.; Gerlt Todd author non-byline.; Gest Amy author non-byline.; Gilson Carla author non-byline.; Goldberger Jeffrey author non-byline.; Goldman Joshua author non-byline.; Groezinger Erich author non-byline.; Guin Jonathan R author non-byline.; Halseth Heather author non-byline.; Hare Joshua author non-byline.; Harness Beth author non-byline.; Hatamiya Nicolas author non-byline.; Haylett Julie author non-byline.; Hazen Neal author non-byline.; Hughes Sean G author non-byline.; Hiroi Yeun author non-byline.; Hockenbrock Amy author non-byline.; Honsvall Amanda author non-byline.; Hopp Jennifer author non-byline.; Howard Julia author non-byline.; Huba Samantha author non-byline.; Husaini Mustafa author non-byline.; Huston Lindsay author non-byline.; Hwang Calvin author non-byline.; Irvin Laura author non-byline.; Iven Val Gene author non-byline.; Jones Robert author non-byline.; Joyce Donald author non-byline.; Karlson Kristine author non-byline.; Kent Jeremy author non-byline.; Klein Christian author non-byline.; Klenck Chris author non-byline.; Kirk Michele author non-byline.; Knight Jordan author non-byline.; Knippa Laura author non-byline.; Knutson Madeleine author non-byline.; Kovacs Louis E author non-byline.; Kuscher Yumi author non-byline.; Kussman Andrea author non-byline.; Landreth Chrissy author non-byline.; Leu Amy author non-byline.; Lothian Dylan author non-byline.; Lowery Maureen author non-byline.; Lukjanczuk Andrew author non-byline.; MacKnight John M author non-byline.; Magee Lawrence M author non-byline.; Magnuson Marja-Liisa author non-byline.; Mares Aaron V author non-byline.; Marquez Anne author non-byline.; McKinley Grant author non-byline.; Meester Scott author non-byline.; Meier Megan author non-byline.; Miles Christopher author non-byline.; Miller Emily author non-byline.; Miller Hannah author non-byline.; Mitrani Raul author non-byline.; Monseau Aaron J author non-byline.; Moorehead Benjamin author non-byline.; Myerburg Robert J author non-byline.; Mytyk Greg author non-byline.; Narver Andrew author non-byline.; Nattiv Aurelia author non-byline.; Nur Laika author non-byline.; Organ Brooke E author non-byline.; Pendergast Meredith author non-byline.; Pettrone Frank A author non-byline.; Pierce Jordan author non-byline.; Poddar Sourav K author non-byline.; Priestman Diana author non-byline.; Quinn Ian author non-byline.; Reifsteck Fred author non-byline.; Restivo Morgan author non-byline.; Robinson James B author non-byline.; Roe Ryan author non-byline.; Rosamond Thomas author non-byline.; Shearer Carrie Rubertino author non-byline.; Riveros Diego author non-byline.; Rueda Miguel author non-byline.; Sakamoto Takamasa author non-byline.; Schnebel Brock author non-byline.; Shah Ankit B author non-byline.; Shahtaji Alan author non-byline.; Shannon Kevin author non-byline.; Sheridan-Young Polly author non-byline.; Soslow Jonathon H author non-byline.; Statuta Siobhan M author non-byline.; Stovak Mark author non-byline.; Tarsici Andrei author non-byline.; Taylor Kenneth S author non-byline.; Terrell Kim author non-byline.; Thomason Matt author non-byline.; Tso Jason author non-byline.; Vigil Daniel author non-byline.; Wang Francis author non-byline.; Winningham Jennifer author non-byline.; Zorn Susanna T author non-byline.;
• Is Part Of: British journal of sports medicine. Volume 56:Issue 16(2022)
• Page Start: 913
• Page End: 918
• Publication Date: 2021-11-01
• Subjects: Covid-19 -- sports; Sports medicine -- Periodicals; 617.1027
• DOI: 10.1136/bjsports-2021-104644
• Languages: English
• ISSNs: 0306-3674

Abstract

Abstract : Objective: To assess the prevalence and clinical implications of persistent or exertional cardiopulmonary symptoms in young competitive athletes following SARS-CoV-2 infection. Methods: This observational cohort study from the Outcomes Registry for Cardiac Conditions in Athletes included 3597 US collegiate athletes after SARS-CoV-2 infection. Clinical characteristics, advanced diagnostic testing and SARS-CoV-2-associated sequelae were compared between athletes with persistent symptoms >3 weeks, exertional symptoms on return to exercise and those without persistent or exertional symptoms. Results: Among 3597 athletes (mean age 20 years (SD, 1 year), 34% female), data on persistent and exertional symptoms were reported in 3529 and 3393 athletes, respectively. Persistent symptoms >3 weeks were present in 44/3529 (1.2%) athletes with 2/3529 (0.06%) reporting symptoms >12 weeks. Exertional cardiopulmonary symptoms were present in 137/3393 (4.0%) athletes. Clinical evaluation and diagnostic testing led to the diagnosis of SARS-CoV-2-associated sequelae in 12/137 (8.8%) athletes with exertional symptoms (five cardiac involvement, two pneumonia, two inappropriate sinus tachycardia, two postural orthostatic tachycardia syndrome and one pleural effusion). No SARS-CoV-2-associated sequelae were identified in athletes with isolated persistent symptoms. Of athletes with chest pain on return to exercise who underwent cardiac MRI (CMR), 5/24 (20.8%) had probable or definite cardiac involvement. In contrast, no athlete with exertional symptoms without chest pain who underwent CMR (0/20) was diagnosed with probable or definite SARS-CoV-2 cardiac involvement. Conclusion: Collegiate athletes with SARS-CoV-2 infection have a low prevalence of persistent or exertional symptoms on return to exercise. Exertional cardiopulmonary symptoms, specifically chest pain, warrant a comprehensive evaluation.