INTERGROWTH-21st Project international INTER-NDA standards for child development at 2 years of age: an international prospective population-based study. Issue 6 (7th June 2020)
- Record Type:
- Journal Article
- Title:
- INTERGROWTH-21st Project international INTER-NDA standards for child development at 2 years of age: an international prospective population-based study. Issue 6 (7th June 2020)
- Main Title:
- INTERGROWTH-21st Project international INTER-NDA standards for child development at 2 years of age: an international prospective population-based study
- Authors:
- Fernandes, Michelle
Villar, José
Stein, Alan
Staines Urias, Eleonora
Garza, Cutberto
Victora, Cesar G
Barros, Fernando C
Bertino, Enrico
Purwar, Manorama
Carvalho, Maria
Giuliani, Francesca
Wulff, Katharina
Abubakar, Amina A
Kihara, Michael
Cheikh Ismail, Leila
Aranzeta, Luis
Albernaz, Elaine
Kunnawar, Naina
Di Nicola, Paola
Ochieng, Roseline
Sandells, Tamsin
Savini, Sandy
Temple, Sophie
Murray, Elizabeth
Ohuma, Eric O
Gravett, Michael G
Pang, Ruyan
Jaffer, Yasmine A
Noble, Julia Alison
Winsey, Adele
Lambert, Ann
Papageorghiou, Aris T
Bhutta, Zulfiqar
Kennedy, Stephen
… (more) - Abstract:
- Abstract : Objectives: To describe the construction of the international INTERGROWTH-21st Neurodevelopment Assessment (INTER-NDA) standards for child development at 2 years by reporting the cognitive, language, motor and behaviour outcomes in optimally healthy and nourished children in the INTERGROWTH-21st Project. Design: Population-based cohort study, the INTERGROWTH-21st Project. Setting: Brazil, India, Italy, Kenya and the UK. Participants: 1181 children prospectively recruited from early fetal life according to the prescriptive WHO approach, and confirmed to be at low risk of adverse perinatal and postnatal outcomes. Primary measures: Scaled INTER-NDA domain scores for cognition, language, fine and gross motor skills and behaviour; vision outcomes measured on the Cardiff tests; attentional problems and emotional reactivity measured on the respective subscales of the preschool Child Behaviour Checklist; and the age of acquisition of the WHO gross motor milestones. Results: Scaled INTER-NDA domain scores are presented as centiles, which were constructed according to the prescriptive WHO approach and excluded children born preterm and those with significant postnatal/neurological morbidity. For all domains, except negative behaviour, higher scores reflect better outcomes and the threshold for normality was defined as ≥10th centile. For the INTER-NDA's cognitive, fine motor, gross motor, language and positive behaviour domains these are ≥38.5, ≥25.7, ≥51.7, ≥17.8 and ≥51.4,Abstract : Objectives: To describe the construction of the international INTERGROWTH-21st Neurodevelopment Assessment (INTER-NDA) standards for child development at 2 years by reporting the cognitive, language, motor and behaviour outcomes in optimally healthy and nourished children in the INTERGROWTH-21st Project. Design: Population-based cohort study, the INTERGROWTH-21st Project. Setting: Brazil, India, Italy, Kenya and the UK. Participants: 1181 children prospectively recruited from early fetal life according to the prescriptive WHO approach, and confirmed to be at low risk of adverse perinatal and postnatal outcomes. Primary measures: Scaled INTER-NDA domain scores for cognition, language, fine and gross motor skills and behaviour; vision outcomes measured on the Cardiff tests; attentional problems and emotional reactivity measured on the respective subscales of the preschool Child Behaviour Checklist; and the age of acquisition of the WHO gross motor milestones. Results: Scaled INTER-NDA domain scores are presented as centiles, which were constructed according to the prescriptive WHO approach and excluded children born preterm and those with significant postnatal/neurological morbidity. For all domains, except negative behaviour, higher scores reflect better outcomes and the threshold for normality was defined as ≥10th centile. For the INTER-NDA's cognitive, fine motor, gross motor, language and positive behaviour domains these are ≥38.5, ≥25.7, ≥51.7, ≥17.8 and ≥51.4, respectively. The threshold for normality for the INTER-NDA's negative behaviour domain is ≤50.0, that is, ≤90th centile. At 22–30 months of age, the cohort overlapped with the WHO motor milestone centiles, showed low postnatal morbidity (<10%), and vision outcomes, attentional problems and emotional reactivity scores within the respective normative ranges. Conclusions: From this large, healthy and well-nourished, international cohort, we have constructed, using the WHO prescriptive methodology, international INTER-NDA standards for child development at 2 years of age. Standards, rather than references, are recommended for population-level screening and the identification of children at risk of adverse outcomes. … (more)
- Is Part Of:
- BMJ open. Volume 10:Issue 6(2020)
- Journal:
- BMJ open
- Issue:
- Volume 10:Issue 6(2020)
- Issue Display:
- Volume 10, Issue 6 (2020)
- Year:
- 2020
- Volume:
- 10
- Issue:
- 6
- Issue Sort Value:
- 2020-0010-0006-0000
- Page Start:
- Page End:
- Publication Date:
- 2020-06-07
- Subjects:
- community child health -- developmental neurology & neurodisability -- paediatrics -- epidemiology
Medicine -- Research -- Periodicals
610.72 - Journal URLs:
- http://www.bmj.com/archive ↗
http://bmjopen.bmj.com/ ↗ - DOI:
- 10.1136/bmjopen-2019-035258 ↗
- Languages:
- English
- ISSNs:
- 2044-6055
- Deposit Type:
- Legaldeposit
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- Available online (eLD content is only available in our Reading Rooms) ↗
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- British Library DSC - BLDSS-3PM
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- 23067.xml