The selection of an optimal segmentation region in physiological signals. (27th March 2022)

• Record Type: Journal Article
• Authors: Oliveira, Jorge; Carvalho, Margarida; Nogueira, Diogo; Coimbra, Miguel
• Other Names: Viana Ana guestEditor.; Marques Inês guestEditor.; Dias Joana Matos guestEditor.
• Is Part Of: International transactions in operational research. Volume 30:Number 1(2023)
• Page Start: 601
• Page End: 618
• Publication Date: 2022-03-27
• Subjects: physiological signals -- deep neural networks -- integer programming -- optimal region selection; Operations research -- Periodicals; 003
• DOI: 10.1111/itor.13138
• Languages: English
• ISSNs: 0969-6016

Abstract

Abstract: Physiological signals are often corrupted by noisy sources. Usually, artificial intelligence algorithms analyze the whole signal, regardless of its varying quality. Instead, experienced cardiologists search for a high‐quality signal segment, where more accurate conclusions can be draw. We propose a methodology that simultaneously selects the optimal processing region of a physiological signal and determines its decoding into a state sequence of physiologically meaningful events. Our approach comprises two phases. First, the training of a neural network that then enables the estimation of the state probability distribution of a signal sample. Second, the use of the neural network output within an integer program. The latter models the problem of finding a time window by maximizing a likelihood function defined by the user. Our method was tested and validated in two types of signals, the phonocardiogram and the electrocardiogram. In phonocardiogram and electrocardiogram segmentation tasks, the system's sensitivity increased on average from 95.1% to 97.5% and from 78.9% to 83.8%, respectively, when compared to standard approaches found in the literature.