Toxicological impact of environmental microplastics and benzo[a]pyrene in the seaworm Hediste diversicolor under environmentally relevant exposure conditions. (1st October 2022)

• Record Type: Journal Article
• Authors: Abouda, Siwar; Missawi, Omayma; Cappello, Tiziana; Boughattas, Iteb; De Marco, Giuseppe; Maisano, Maria; Banni, Mohamed
• Is Part Of: Environmental pollution. Volume 310(2022)
• Publication Date: 2022-10-01
• Subjects: Environmental MPs -- Polycyclic aromatic hydrocarbons -- Polychaete -- Trojan horse effect -- Toxicological response; Pollution -- Periodicals; Pollution -- Environmental aspects -- Periodicals; Environmental Pollution -- Periodicals; Pollution -- Périodiques; Pollution -- Aspect de l'environnement -- Périodiques; Pollution -- Effets physiologiques -- Périodiques; Pollution; Pollution -- Environmental aspects; Periodicals; Electronic journals; 363.73
• DOI: 10.1016/j.envpol.2022.119856
• Languages: English
• ISSNs: 0269-7491

Abstract

Abstract: Nowadays, marine ecosystems are under severe threat from the simultaneous presence of multiple stressors, including microplastics (MPs) and polycyclic aromatic hydrocarbons (PAHs) such as benzo[a]pyrene (B[a]P). In addition to their presence in various marine compartments, there are increasing concerns on the potential capacity of MPs to sorb, concentrate and transfer these pollutants in the environment. Although their ecotoxicological impacts are currently evident, few works have studied the combined effects of these contaminants. Therefore, the major purpose of this work was to assess the toxicity of environmental relevant concentrations of MPs (<30 μm) and B[a]P, alone and in mixture, in the seaworm Hediste diversicolor by exploring their accumulation and hazardous biological effects for 3 and 7 days. Environmental MPs were able to increase B[a]P in a time-dependent manner. The obtained results showed that individual treatments, as well as co-exposure to contaminants, caused cytotoxicity and genotoxicity in the cœlomic fluid cells, while oxidative stress effects were observed at tissue and gene levels associated with alteration in neurotransmission. Overall, our findings provide additional clues about MPs as organic pollutant vectors in the marine environment, and contribute to a clearer understanding of their toxicological risk to aquatic invertebrates. Graphical abstract: Image 1 Highlights: Impact of environmental MPs (<30 μm) and B[a]P was assessed on seaworms. MPs and B[a]P trigger instability of cœlomocyte lysosomal membranes. MPs and B[a]P induce oxidative stress and neurotransmission disorders.