Trabecular-Iris Circumference Volume in Open Angle Eyes Using Swept-Source Fourier Domain Anterior Segment Optical Coherence Tomography. (19th August 2014)

• Record Type: Journal Article
• Authors: Rigi, Mohammed; Blieden, Lauren S.; Nguyen, Donna; Chuang, Alice Z.; Baker, Laura A.; Bell, Nicholas P.; Lee, David A.; Mankiewicz, Kimberly A.; Feldman, Robert M.
• Other Names: Mookherjee Suddhasil Academic Editor.
• Is Part Of: Journal of ophthalmology. Volume 2014(2014)
• Publication Date: 2014-08-19
• Subjects: Ophthalmology -- Periodicals; Eye Diseases; Ophthalmology; Ophthalmology; Electronic journals; Periodicals; Periodicals; Fulltext; Internet Resources; Periodicals; 617.7
• DOI: 10.1155/2014/590978
• Languages: English
• ISSNs: 2090-004X

Abstract

Abstract : Purpose . To introduce a new anterior segment optical coherence tomography parameter, trabecular-iris circumference volume (TICV), which measures the integrated volume of the peripheral angle, and establish a reference range in normal, open angle eyes. Methods . One eye of each participant with open angles and a normal anterior segment was imaged using 3D mode by the CASIA SS-1000 (Tomey, Nagoya, Japan). Trabecular-iris space area (TISA) and TICV at 500 and 750 µ m were calculated. Analysis of covariance was performed to examine the effect of age and its interaction with spherical equivalent. Results . The study included 100 participants with a mean age of 50 (±15) years (range 20–79). TICV showed a normal distribution with a mean (±SD) value of 4.75 µ L (±2.30) for TICV500 and a mean (±SD) value of 8.90 µ L (±3.88) for TICV750. Overall, TICV showed an age-related reduction ( P = 0.035 ) . In addition, angle volume increased with increased myopia for all age groups, except for those older than 65 years. Conclusions . This study introduces a new parameter to measure peripheral angle volume, TICV, with age-adjusted normal ranges for open angle eyes. Further investigation is warranted to determine the clinical utility of this new parameter.