Visual electrophysiology and neuropsychology in bipolar disorders: A review on current state and perspectives. (September 2022)

• Record Type: Journal Article
• Authors: Tursini, Katelyne; Le Cam, Steven; Schwan, Raymund; Gross, Grégory; Angioi-Duprez, Karine; Conart, Jean-Baptiste; Remy, Irving; Bernardin, Florent; Laprévote, Vincent; Knobloch, Eléa; Ricaud, Tiphaine; Rahnema, Aline; Louis-Dorr, Valérie; Schwitzer, Thomas
• Is Part Of: Neuroscience and biobehavioral reviews. Volume 140(2022)
• Publication Date: 2022-09
• Subjects: ANN Artificial Neural Networks -- BD Bipolar Disorders -- BD1 Bipolar Disorders type 1 -- BD2 Bipolar Disorders type 2 -- CAMCOG Cambridge Cognition Examination -- CANTAB Cambridge Neuropsychological Test Automated Battery -- CNS Central Nervous System -- CPT Continuous Performance Test -- CVEP Cortical Visual Evoked Potentials -- CVLT California Verbal Learning Test -- ECG Electrocardiogram -- EEG Electroencephalogram -- EF Executive Functions -- ERG Electroretinogram -- ERP Event Related Potentials -- fERG Flash-Electroretinogram -- GABA Gamma-Aminobutyric Acid -- GBS Gottfries-Bråne-Steen -- GDS Global Deterioration Scale -- HC Healthy Controls -- ISCEV International Society for Clinical Electrophysiology of Vision -- MDD Major Depressive Disorder -- MMN Mismatch Negativity -- MMSE Mini Mental State Evaluation -- NART National Adult Reading Test -- PERG Pattern-Electroretinogram -- RAVLT Ray Auditory Verbal Learning Test -- SZ Schizophrenia -- TAP Test of Attentional Performance -- TOM Theory Of Mind -- TMT Trail Making Test -- VEP Visual Evoked Potentials -- WAIS Weschler Adult Intelligence Scale -- WAIS-R Weschler Adult Intelligence Scale-Revised -- WCST Wisconsin Card Sorting Test -- WHO World Health Oganization -- WMS-R Weschler Memory Scale-Revised -- YMRS Young Mania Rating Scale; Electroretinogram -- Visual Evoked Potential -- Bipolar disorder -- Neuropsychology -- Cognitive impairment -- Biomarker -- Retina; Psychophysiology -- Periodicals; Human behavior -- Periodicals; Animal behavior -- Periodicals; Neurology -- Periodicals; Behavior -- Periodicals; Ethology -- Periodicals; Neurology -- Periodicals; Psychophysiologie -- Périodiques; Comportement humain -- Périodiques; Animaux -- Mœurs et comportement -- Périodiques; Neurologie -- Périodiques; Animal behavior; Human behavior; Neurology; Psychophysiology; Periodicals; Electronic journals; 573.8
• DOI: 10.1016/j.neubiorev.2022.104764
• Languages: English
• ISSNs: 0149-7634

Abstract

Abstract: Bipolar disorder is a lifelong condition. Today, there is a urgent need to find indicators of the disease. Specifically, they could be useful to improve the diagnosis and the early detection, the prognosis, to estimate the treatment response and to create homogeneous subgroups of patients based on similar pathophysiological mechanisms. Here, we assume that visual electrophysiology in combination with a neuropsychological assessment can give additional data to routine practice, especially to precise specific damages and pathophysiological characteristics of these patients. Visual electrophysiology is characterized by an electroretinogram and the delivery of visual evoked potentials, which measure retinal and visual cortical neuronal functioning in response to visual stimulations. This review highlights the interest of visual electrophysiology and neuropsychology performed in isolation and to present the benefits of combining these measures. We will review the results based on these measures in patients with bipolar disorders. Finally, we argue for the use of innovative techniques such as signal processing and artificial intelligence techniques for routine care and precision medicine in bipolar disorders. Highlights: Visual electrophysiology abnormalities are present in bipolar patients. The neurocognitive profile of these patients is hard to be clearly defined. Visual electrophysiology and neuropsychology are two complementary measures. Coupling these measures would be a step toward precision psychiatry. The help of artificial intelligence would help to highlight additional indicators.