Diagnostic measure to quantify loss of clinical components in multi‐lead electrocardiogram. Issue 1 (23rd February 2016)

• Record Type: Journal Article
• Authors: Tripathy, R.K.; Sharma, L.N.; Dandapat, S.
• Is Part Of: Healthcare technology letters. Volume 3:Issue 1(2016)
• Page Start: 61
• Page End: 66
• Publication Date: 2016-02-23
• Subjects: electrocardiography -- medical signal processing -- principal component analysis; Pearson linear correlation coefficient -- Spearman rank‐order correlation coefficient -- wavelet energy diagnostic distortion -- weighted diagnostic distortion -- MECG data reduction scheme -- MECG enhancement -- weighted percentage root mean square difference -- MECG signals -- multilead electrocardiogram signals -- clinical components -- principal component‐based diagnostic measure; Biomedical engineering -- Periodicals; Medical technology -- Periodicals; 610.28
• DOI: 10.1049/htl.2015.0011
• Languages: English
• ISSNs: 2053-3713

Abstract

Abstract : In this Letter, a novel principal component (PC)‐based diagnostic measure (PCDM) is proposed to quantify loss of clinical components in the multi‐lead electrocardiogram (MECG) signals. The analysis of MECG shows that, the clinical components are captured in few PCs. The proposed diagnostic measure is defined as the sum of weighted percentage root mean square difference (PRD) between the PCs of original and processed MECG signals. The values of the weight depend on the clinical importance of PCs. The PCDM is tested over MECG enhancement and a novel MECG data reduction scheme. The proposed measure is compared with weighted diagnostic distortion, wavelet energy diagnostic distortion and PRD. The qualitative evaluation is performed using Spearman rank‐order correlation coefficient (SROCC) and Pearson linear correlation coefficient. The simulation result demonstrates that the PCDM performs better to quantify loss of clinical components in MECG and shows a SROCC value of 0.9686 with subjective measure.