Assessing the importance of Molecular and Genetic perspectives in Prophesying the KFD transmission risk provinces in the Western Ghats, Kerala, INDIA in context with spatial distribution, Extensive genetic Diversity, and phylogeography. (June 2021)

• Record Type: Journal Article
• Authors: Anoopkumar, A.N.; Aneesh, Embalil Mathachan
• Is Part Of: Comparative immunology, microbiology and infectious diseases. Volume 76(2021)
• Publication Date: 2021-06
• Subjects: Spatial distribution -- Haemaphysalis -- Kyasarnur forest disease genetic diversity -- Western Ghats -- KFD; Communicable diseases in animals -- Periodicals; Veterinary immunology -- Periodicals; Veterinary microbiology -- Periodicals; Immunology -- Periodicals; Microbiology -- Periodicals; Communicable diseases -- Periodicals; Communicable Diseases -- immunology -- Periodicals; Communicable Diseases -- veterinary -- Periodicals; Allergy and Immunology -- Periodicals; Microbiology -- Periodicals; Veterinary Medicine -- Periodicals; Immunologie -- Périodiques; Microbiologie -- Périodiques; Maladies infectieuses -- Périodiques; Communicable diseases; Immunology; Microbiology; Electronic journals; Periodicals; 636.08969
• DOI: 10.1016/j.cimid.2021.101652
• Languages: English
• ISSNs: 0147-9571

Abstract

Highlights: Even in developing countries like India, KFD remain challenges that mandate attention from health authorities. The infection has a socioeconomic effect on the livelihood communities of individuals who are relying on the forest area. The genetic data for Haemaphysalis bispinosa was comparatively available in sufficient extent than the other species . The molecular analysis revealed that the Karnataka and Maharashtra states were more vulnerable to KFD infection. Abstract: The deadly effects of KFD have been pointed in southern India; however, the infecting regions have been getting larger in recent epochs. People who live or work in regions where KFDV infected tick vectors are present are severely prone to procuring the infection. Being aware of tick vectors and infectious agents' geospatial location is vital to direct sustenance approaches to prevent and manage such infectious diseases as KFD. The present investigation has focussed on the spatial distribution, Extensive genetic Diversity, and phylogeography to forecast the probable KFD disease risk provinces in the Western Ghats. The statistical analysis for diversity indices and community comparison has been performed by using SPSS version 24.0.0 and R software version 3.4.2. The nucleotide sequences of the respective ticks and KFDV were retrieved from NCBI. The first strand of this investigation revealed that, around the world, the Indian province was found to exhibit a maximum range of diversity for tick vectors. The next strands prophesied the KFD transmission risk areas in the Western Ghats region, India, with computational spatial analysis and phylogeography. The final strand exposed the genetic diversity of the KFD virus and the tick vectors in terms of their spatial distribution worldwide.