Synthesis of novel 6-piperidin-1-ylpyrimidine-2, 4-diamine 3-oxide substituted calix[4]arene as a highly selective and sensitive fluorescent sensor for Cu2+ in aqueous samples. Issue 13 (26th March 2020)

• Record Type: Journal Article
• Authors: Akbarzadeh, Ali; Zadmard, Reza; Jalali, Mohammad Reza
• Is Part Of: Tetrahedron letters. Volume 61:Issue 13(2020)
• Publication Date: 2020-03-26
• Subjects: Supramolecular chemistry -- Noncovalent interactions -- Host-guest chemistry -- Fluorescent chemosensors -- Calix[4]arenes -- Minoxidil -- Copper ion recognition; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2020.151658
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Highlights: Novel 6-piperidin-1-ylpyrimidine-2, 4-diamine 3-oxide substituted calix[4]arene. A highly selective and sensitive fluorescent sensor for Cu 2+ . The structure of the target molecule was determined by HRMS, 1 H NMR, 13 C NMR and FT-IR. Abstract: In this study, we designed and synthesized a novel sensitive fluorescent sensor for Cu 2+ cation by attaching two minoxidil molecules at the lower-rim of calix[4]arene annulus via the formation of two urea linkages. This chemosensor can selectively recognize Cu 2+ in EtOH containing 5% H2 O through a significant decline in fluorescence emission. The structure of the target molecule was determined by HRMS, 1 H NMR, 13 C NMR and FT-IR.