Are we over-treating hypoxic spells in preterm infants?. Issue 3 (June 2021)

• Record Type: Journal Article
• Authors: Conlon, Steven; Di Fiore, Juliann M.; Martin, Richard J.
• Is Part Of: Seminars in fetal & neonatal medicine. Volume 26:Issue 3(2021)
• Publication Date: 2021-06
• Subjects: Apnea of prematurity -- Intermittent hypoxemia -- Caffeine therapy -- Supplemental oxygen; Neonatology -- Periodicals; Newborn infants -- Diseases -- Periodicals; Fetus -- Diseases -- Periodicals; 618.9201
• DOI: 10.1016/j.siny.2021.101227
• Languages: English
• ISSNs: 1744-165X

Abstract

Abstract: A frequent challenge in Neonatology is the high frequency of spontaneously occurring hypoxemic events, a majority of which are associated with apnea or hypoventilation. These episodes present a challenge for caregivers and families as they frequently delay discharge of preterm infants. Supplemental oxygen, respiratory support, and caffeine therapy are widely used as therapeutic approaches, but challenges remain regarding their precise indications. Future clinical practice should be directed by an evidence-based approach including automated supplemental oxygen, minimizing the use of medications for gastroesophageal reflux, optimal timing and dosage of caffeine therapy, and standardization of alarm limits and discharge monitoring protocols.