Automated inter-patient seizure detection using multichannel Convolutional and Recurrent Neural Networks. (February 2021)

• Record Type: Journal Article
• Authors: Craley, Jeff; Johnson, Emily; Jouny, Christophe; Venkataraman, Archana
• Is Part Of: Biomedical signal processing and control. Volume 64(2021)
• Publication Date: 2021-02
• Subjects: Epilepsy -- Seizure detection -- Convolutional Neural Networks -- Long Short-Term Memory networks; Signal processing -- Periodicals; Biomedical engineering -- Periodicals; Signal Processing, Computer-Assisted -- Periodicals; Image Processing, Computer-Assisted -- Periodicals; Biomedical Engineering -- Periodicals; 610.28
• DOI: 10.1016/j.bspc.2020.102360
• Languages: English
• ISSNs: 1746-8094

Abstract

Abstract: We present an end-to-end deep learning model that can automatically detect epileptic seizures in multichannel electroencephalography (EEG) recordings. Our model combines a Convolutional Neural Network (CNN) and a Bidirectional Long Short-Term Memory (BLSTM) network to efficiently mine information from the EEG data using a small number of trainable parameters. Specifically, the CNN learns a latent encoding for each one second window of raw multichannel EEG data. In conjunction, the BLSTM learns the temporal evolution of seizure presentations given the CNN encodings. The combination of these architectures allows our model to capture both the short time scale EEG features indicative of seizure activity as well as the long term correlations in seizure presentations. Unlike most prior work in seizure detection, we mimic an in-patient monitoring setting through a leave-one-patient-out cross validation procedure, attaining an average seizure detection sensitivity of 0.91 across all patients. This strategy verifies that our model can generalize to new patients. We demonstrate that our CNN–BLSTM outperforms both conventional feature extraction methods and state-of-the-art deep learning approaches that rely on larger and more complex network architectures. Graphical abstract: Highlights: CNN–BLSTM network for seizure detection in long term epilepsy monitoring. Description of end-to-end training methods for the CNN–BLSTM network. Comparisons to popular alternative approaches from deep learning and signal processing. Inter-patient evaluation in a challenging dataset of focal epilepsy patients.