The role of metal ions in the Golgi apparatus. (13th July 2022)

• Record Type: Journal Article
• Authors: Gao, Jiayin; Gao, Anbo; Zhou, Hong; Chen, Linxi
• Is Part Of: Cell biology international. Volume 46:Number 9(2022)
• Page Start: 1309
• Page End: 1319
• Publication Date: 2022-07-13
• Subjects: Ca2+ -- Cu -- Golgi apparatus -- metal ions -- Zn2+; Cytology -- Periodicals; Cells -- Periodicals; 571.605
• DOI: 10.1002/cbin.11848
• Languages: English
• ISSNs: 1065-6995

Abstract

Abstract: The Golgi apparatus is a membrane‐bound organelle that functions as a central role in the secretory pathway. Since the discovery of the Golgi apparatus, its structure and function have attracted ever‐increasing attention from researchers. Recently, it has been demonstrated that metal ions are necessary for the Golgi apparatus to maintain its proper structure and functions. Given that metal ions play an important role in various biological processes, their abnormal homeostasis is related to many diseases. Therefore, in this paper, we reviewed the uptake and release mechanisms of the Golgi apparatus Ca 2+, Cu, and Zn 2+ . Furthermore, we describe the diseases associated with Golgi apparatus Ca 2+, Cu, and Zn 2+ imbalance.