Effects of age and gender on neural correlates of emotion imagery. Issue 13 (12th May 2022)

• Record Type: Journal Article
• Authors: Tomasino, Barbara; Maggioni, Eleonora; Bonivento, Carolina; Nobile, Maria; D'Agostini, Serena; Arrigoni, Filippo; Fabbro, Franco; Brambilla, Paolo
• Is Part Of: Human brain mapping. Volume 43:Issue 13(2022)
• Page Start: 4116
• Page End: 4127
• Publication Date: 2022-05-12
• Subjects: age -- emotion -- fMRI -- gender -- imagery -- limbic system; Brain mapping -- Periodicals; 611.81
• DOI: 10.1002/hbm.25906
• Languages: English
• ISSNs: 1065-9471

Abstract

Abstract: Mental imagery is part of people's own internal processing and plays an important role in everyday life, cognition and pathology. The neural network supporting mental imagery is bottom‐up modulated by the imagery content. Here, we examined the complex associations of gender and age with the neural mechanisms underlying emotion imagery. We assessed the brain circuits involved in emotion mental imagery (vs. action imagery), controlled by a letter detection task on the same stimuli, chosen to ensure attention to the stimuli and to discourage imagery, in 91 men and women aged 14–65 years using fMRI. In women, compared with men, emotion imagery significantly increased activation within the right putamen, which is involved in emotional processing. Increasing age, significantly decreased mental imagery‐related activation in the left insula and cingulate cortex, areas involved in awareness of ones' internal states, and it significantly decreased emotion verbs‐related activation in the left putamen, which is part of the limbic system. This finding suggests a top‐down mechanism by which gender and age, in interaction with bottom‐up effect of type of stimulus, or directly, can modulate the brain mechanisms underlying mental imagery. Abstract : In the study we explored the influences of gender and age on the neural circuits involved in mental imagery.