Rapid Antigen Diagnostics as Frontline Testing in the COVID‐19 Pandemic. Issue 8 (5th July 2022)

• Record Type: Journal Article
• Authors: Xu, Jiang; Kerr, Liam; Jiang, Yue; Suo, Wenhao; Zhang, Lei; Lao, Taotao; Chen, Yuxin; Zhang, Yan
• Is Part Of: Small science. Volume 2:Issue 8(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-07-05
• Subjects: antigen tests -- COVID-19 -- in vitro diagnostics -- immnuoassays; Nanoscience -- Periodicals; Nanotechnology -- Periodicals; 620.5
• DOI: 10.1002/smsc.202200009
• Languages: English
• ISSNs: 2688-4046

Abstract

Abstract : The ongoing global COVID‐19 pandemic, caused by the SARS‐CoV‐2 virus, has resulted in significant loss of life since December 2019. Timely and precise virus detection has been proven as an effective solution to reduce the spread of the virus and to track the epidemic. Rapid antigen diagnostics has played a significant role in the frontline of COVID‐19 testing because of its convenience, low cost, and high accuracy. Herein, different types of recently innovated in‐lab and commercial antigen diagnostic technologies with emphasis on the strengths and limitations of these technologies including the limit of detection, sensitivity, specificity, affordability, and usability are systematically reviewed. The perspectives of assay development are looked into. Abstract : Antigen test kits play important roles in the frontline of COVID‐19 testing because of their convenience, low cost, and high accuracy. Herein, different types of recently innovated in‐lab and commercial antigen diagnostic technologies with emphasis on the strengths and limitations of these technologies including the limit of detection, sensitivity, specificity, affordability, and usability are systematically reviewed.