Biocompatible and photocrosslinkable poly(ethylene glycol)/keratin biocomposite hydrogels. Issue 15 (13th October 2021)

• Record Type: Journal Article
• Authors: Wang, Chenshu; Wang, Lijuan; Wan, Xiuzhen; Jiang, Xuefeng; Yuan, Jiang
• Is Part Of: Journal of biomaterials science. Volume 32:Issue 15(2021)
• Page Start: 1998
• Page End: 2008
• Publication Date: 2021-10-13
• Subjects: Methacrylated keratin -- hydrogel -- photocrosslinking -- PEGDMA -- biocompatibility; Polymers -- Biocompatibility -- Periodicals; Biomedical materials -- Periodicals; 572.33
• DOI: 10.1080/09205063.2021.1952384
• Languages: English
• ISSNs: 0920-5063

Abstract

Abstract: A biocompatible hydrogel is ideal for tissue engineering and regeneration. In this study, methacrylated keratin (KerMA) was synthesized for the first time and then blended with poly(ethylene glycol dimethacrylate) (PEGDMA) to form hydrogel through photocrosslinking. The chemical structure, gelation time, swelling behavior, hydrophilicity, cytotoxicity, and 3D printability of PEGDMA/KerMA hydrogels were characterized and exploited. The PEGDMA/KerMA hydrogels performed good cytocompatibility, providing potential applications for tissue engineering and regenerative medicine.