Diagnostic Accuracy of Wireless Capsule Endoscopy in Polyp Recognition Using Deep Learning: A Meta-Analysis. (19th March 2022)

• Record Type: Journal Article
• Authors: Mi, Junjie; Han, Xiaofang; Wang, Rong; Ma, Ruijun; Zhao, Danyu
• Other Names: B. D. Parameshachari Academic Editor.
• Is Part Of: International journal of clinical practice. Volume 2022(2022)
• Publication Date: 2022-03-19
• Subjects: Clinical medicine -- Periodicals; Medicine -- Periodicals; 610.5
• DOI: 10.1155/2022/9338139
• Languages: English
• ISSNs: 1368-5031

Abstract

Abstract : Aim . As the completed studies have small sample sizes and different algorithms, a meta-analysis was conducted to assess the accuracy of WCE in identifying polyps using deep learning. Method . Two independent reviewers searched PubMed, Embase, the Web of Science, and the Cochrane Library for potentially eligible studies published up to December 8, 2021, which were analysed on a per-image basis. STATA RevMan and Meta-DiSc were used to conduct this meta-analysis. A random effects model was used, and a subgroup and regression analysis was performed to explore sources of heterogeneity. Results . Eight studies published between 2017 and 2021 included 819 patients, and 18, 414 frames were eventually included in the meta-analysis. The summary estimates for the WCE in identifying polyps by deep learning were sensitivity 0.97 (95% confidence interval (CI), 0.95–0.98); specificity 0.97 (95% CI, 0.94–0.98); positive likelihood ratio 27.19 (95% CI, 15.32–50.42); negative likelihood ratio 0.03 (95% CI 0.02–0.05); diagnostic odds ratio 873.69 (95% CI, 387.34–1970.74); and the area under the sROC curve 0.99. Conclusion . WCE uses deep learning to identify polyps with high accuracy, but multicentre prospective randomized controlled studies are needed in the future.