Uptake of Functional Ultrasmall Gold Nanoparticles in 3D Gut Cell Models (Small 31/2022). Issue 31 (4th August 2022)

• Record Type: Journal Article
• Authors: Sokolova, Viktoriya; Ebel, Jana‐Fabienne; Kollenda, Sebastian; Klein, Kai; Kruse, Benedikt; Veltkamp, Claudia; Lange, Christian M.; Westendorf, Astrid M.; Epple, Matthias
• Is Part Of: Small. Volume 18:Issue 31(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-08-04
• Subjects: cancer -- cytotoxicity -- gold nanoparticles -- gut organoids -- spheroids -- tumors -- uptake; Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.202270168
• Languages: English
• ISSNs: 1613-6810

Abstract

Abstract : Ultrasmall Gold Nanoparticles Three‐dimensional cell culture models represent a bridge between conventional two‐dimensional cell culture studies and in‐vivo animal experiments. In article number 2201167, Astrid M. Westendorf, Matthias Epple, and co‐workers demonstrate the cytostatic action of doxorubicin‐carrying ultrasmall gold nanoparticles, including their superior ability to enter the three‐dimensional cell cultures compared to dissolved drugs.