The Antigastric Cancer Activity of San Leng Powder Extract Induces Apoptosis in Balb/C Bearing-SGC-7901 Mice. (8th May 2017)

• Record Type: Journal Article
• Authors: Yu, Chen; Ji, Ai-Jun; Lu, Jian-Wei; Liu, Shi-Jia; Sun, Yu
• Other Names: Cherniack Evan P. Academic Editor.
• Is Part Of: Evidence-based complementary and alternative medicine. Volume 2017(2017)
• Publication Date: 2017-05-08
• Subjects: Alternative medicine -- Periodicals; 615.505
• DOI: 10.1155/2017/1052125
• Languages: English
• ISSNs: 1741-427X

Abstract

Abstract : San Leng powder extract has been used as medicinal compound for the prevention and treatment of cancers. The antitumor activity of SLPE was determined by treating BALB/C mice harboring a human gastric cancer xenograft with SPLE for 17 days. Mice were also treated with fluorouracil (5-Fu, 25 mg/kg) or a combination of SLPE and 5-Fu. Our results indicate that the inhibition of tumor growth by SLPE might be due to a block in the cell cycle and the induction of apoptosis. These results suggest that SLPE might be useful in the treatment of gastric cancer.