A dual-responsive doxorubicin–indoximod conjugate for programmed chemoimmunotherapy. Issue 7 (15th June 2022)
- Record Type:
- Journal Article
- Title:
- A dual-responsive doxorubicin–indoximod conjugate for programmed chemoimmunotherapy. Issue 7 (15th June 2022)
- Main Title:
- A dual-responsive doxorubicin–indoximod conjugate for programmed chemoimmunotherapy
- Authors:
- Yang, Zhaoxuan
Huang, Jiaqi
Lin, Yaying
Luo, Xiangjie
Lin, Haojin
Lin, Hongyu
Gao, Jinhao - Abstract:
- Abstract : A dual-responsive doxorubicin–indoximod conjugate was developed, which allows for sequential on-demand release of doxorubicin and indoximod for programmed chemoimmunotherapy. Abstract : Herein we report a dual-responsive doxorubicin–indoximod conjugate (DOXIND) for programmed chemoimmunotherapy. This conjugate is able to release doxorubicin and indoximod upon exposure to appropriate stimuli for synergistic chemotherapy and immunotherapy, respectively. We demonstrate its promoting effects on immune response and inhibiting effects on tumor growth through a series of in vitro and in vivo experiments.
- Is Part Of:
- RSC chemical biology. Volume 3:Issue 7(2022)
- Journal:
- RSC chemical biology
- Issue:
- Volume 3:Issue 7(2022)
- Issue Display:
- Volume 3, Issue 7 (2022)
- Year:
- 2022
- Volume:
- 3
- Issue:
- 7
- Issue Sort Value:
- 2022-0003-0007-0000
- Page Start:
- 853
- Page End:
- 858
- Publication Date:
- 2022-06-15
- Subjects:
- 572
- Journal URLs:
- https://pubs.rsc.org/en/journals/journalissues/cb#!recentarticles&adv ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/d1cb00257k ↗
- Languages:
- English
- ISSNs:
- 2633-0679
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 22965.xml