Zn(II) and Co(II)-based coordination polymers: anesthesia effect by regulating animal blood pressure in hip replacement operation. Issue 4 (3rd April 2021)

• Record Type: Journal Article
• Authors: Bao, Cai-Ying; Zheng, Yan-Ya; Zhang, Huan; Zhuo, Qian
• Is Part Of: Inorganic and nano-metal chemistry. Volume 51:Issue 4(2021)
• Page Start: 531
• Page End: 537
• Publication Date: 2021-04-03
• Subjects: Coordination polymers -- anesthesia effect -- hip replacement; Inorganic compounds -- Synthesis -- Periodicals; Nanostructured materials -- Periodicals; Reactivity (Chemistry) -- Periodicals; Inorganic compounds -- Synthesis; Nanostructured materials; Reactivity (Chemistry); Periodicals; 546
• DOI: 10.1080/24701556.2020.1799398
• Languages: English
• ISSNs: 2470-1556

Abstract

Abstract: Two new transition coordination polymers (CPs) with the chemical formula of {[Zn4 (dip)4 (H2 O)2 (4-ppbp)2 ]· 12H2 O} n (1, H2 dpa = diphenic acid, 4-ppbp = (propane-1, 3-diylbis(piperazine-4, 1-diyl))bis(pyridin-4-ylmethanone)) and [Co(dipH)2 (bdin)] n (2, bdin = N, N-(butane-1, 3-diyl)diisonicotinamide) have been successfully prepared by reaction of the corresponding metal salts with the H2 dpa ligand in the presence of different flexible dipyridylamide ligands. Its treatment activity combined with epidural anesthesia for hip replacement was evaluated. First, the hip replacement operation was carried on experimental mice, followed by the compound given combined with epidural anesthesia. The animal survival rate as well as the rate of anesthesia was recorded and analyzed. In addition to this, the blood pressure level of the mice was also determined throughout the procession of the hip replacement operation.