Pauson‐Khand Reactions with Concomitant C−O Bond Cleavage for the Preparation of 5, 5‐ 5, 6‐ and 5, 7‐Bicyclic Ring Systems. Issue 7 (16th February 2021)

• Record Type: Journal Article
• Authors: Ma, Ding; Hu, Naifeng; Ao, Junli; Zang, Shaoli; Yu, Guo; Liang, Guangxin
• Is Part Of: Advanced synthesis & catalysis. Volume 363:Issue 7(2021)
• Page Start: 1887
• Page End: 1891
• Publication Date: 2021-02-16
• Subjects: Pauson-Khand reaction -- cyclopentenone -- cobalt catalysis -- C−O bond cleavage -- bicyclo-carbocycles; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.202001311
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: Pauson‐Khand reactions (PKR) with concomitant C−O bond cleavage have been developed for construction of 5, 5‐ 5, 6‐ and 5, 7‐bicyclic ring systems bearing complex stereochemistry. The chemistry generates intermolecular PKR‐type products in an absolute regio‐ and stereochemical control which is hardly achievable through real intermolecular Pauson‐Khand reactions. A mechanism for this Pauson‐Khand reaction has been proposed based on deuterium labelling experiments. Abstract :