Multicomponent synthesis of highly functionalized piperidines. Issue 6 (19th March 2021)

• Record Type: Journal Article
• Authors: Ardakani, Leili Shaker; Arabmarkadeh, Arash; Kazemi, Mosstafa
• Is Part Of: Synthetic communications. Volume 51:Issue 6(2021)
• Page Start: 856
• Page End: 879
• Publication Date: 2021-03-19
• Subjects: Highly functionalized piperidines -- medicinal chemistry -- drug discovery -- synthetic chemistry; Organic compounds -- Synthesis -- Periodicals; Chemistry, Organic; Synthesis; 547.205
• DOI: 10.1080/00397911.2020.1861301
• Languages: English
• ISSNs: 0039-7911

Abstract

Abstract: Highly functionalized piperidines are a versatile class of nitrogen-containing heterocycles which find broad applications in numerous fields such as medicinal chemistry and drug discovery research. The synthesis of this privileged scaffold from readily available materials remains is a hot topic research for the synthetic chemistry community. This review aims to describe the different strategies developed so far for the synthesis of highly functionalized piperidines. Graphical Abstract: UF0001