Enantiopure chiroptical probes for circular dichroism and absorbance based detection of nerve gas simulants. Issue 64 (21st July 2022)

• Record Type: Journal Article
• Authors: Debnath, Snehasish; Chatterjee, Pabitra B.
• Is Part Of: Chemical communications. Volume 58:Issue 64(2022)
• Page Start: 9006
• Page End: 9009
• Publication Date: 2022-07-21
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d2cc03392e
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : In this work, we describe a family of enantiopure chiroptical vanadium compounds functioning as probes for an organophosphorus compound and its bimodal detection using the combination of circular dichroism and UV/vis techniques. Abstract : A series of oxovanadium(v ) compounds 1–4 were prepared and explored as stereodynamic chiroptical probes to detect a simulant of sarin known as diethyl chlorophosphate (DCP) without any interference from the competing analytes. Simultaneous CD cum UV/vis based bimodal instant recognition of DCP using optically active probes is unprecedented. Upon fabricating the vanadium compound with a polymer has yielded a chiroptical membrane, which showed a change in its dichroic as well as colorimetric signals on interaction with DCP vapour at 1 ppm. EPR and UV/vis studies revealed an irreversible change of the CD-active V(v ) to the CD-silent ternary V(v ) species in presence of DCP via a transient V(iv ) species. Nucleophilic attack of the alkoxo oxygen of 1–4 to the electrophilic P atom of DCP resulted in the formation of ternary V(v ) compounds as confirmed by 51 V/ 31 P NMR.