Selection and characterisation of bioreceptors to develop nanoparticle-based lateral-flow immunoassays in the context of the SARS-CoV-2 outbreak. Issue 16 (29th July 2022)

• Record Type: Journal Article
• Authors: Hu, Liming; Calucho, Enric; Fuentes-Chust, Celia; Parolo, Claudio; Idili, Andrea; Álvarez-Diduk, Ruslan; Rivas, Lourdes; Merkoçi, Arben
• Is Part Of: Lab on a chip. Volume 22:Issue 16(2022)
• Page Start: 2938
• Page End: 2943
• Publication Date: 2022-07-29
• Subjects: Miniature electronic equipment -- Periodicals; Combinatorial chemistry -- Periodicals; Biotechnology -- Periodicals; 543.0813
• DOI: 10.1039/d2lc00486k
• Languages: English
• ISSNs: 1473-0197

Abstract

Abstract : Selection of bioreceptors is a resource- and time-consuming process that holds back the highly demanded implementation of rapid tests in emergency situations. Abstract : This manuscript aims at raising the attention of the scientific community to the need for better characterised bioreceptors for fast development of point-of-care diagnostic devices able to support mass frequency testing. Particularly, we present the difficulties encountered in finding suitable antibodies for the development of a lateral flow assay for detecting the nucleoprotein of SARS-CoV-2.