Evaluation of Antioxidant Capacity of Solanum sessiliflorum (Cubiu) Extract: An In Vitro Assay. (15th December 2015)

• Record Type: Journal Article
• Authors: Mascato, Diego Rocha de Lucena Herrera; Monteiro, Janice B.; Passarinho, Michele M.; Galeno, Denise Morais Lopes; Cruz, Rubén J.; Ortiz, Carmen; Morales, Luisa; Lima, Emerson Silva; Carvalho, Rosany Piccolotto
• Other Names: Johnston C. S. Academic Editor.
• Is Part Of: Journal of nutrition and metabolism. Volume 2015(2015)
• Publication Date: 2015-12-15
• Subjects: Nutrition -- Periodicals; Metabolism -- Periodicals; Diet in disease -- Periodicals; Metabolic Diseases; Metabolism; Nutrition Disorders; Nutritional Sciences; Diet in disease; Metabolism; Nutrition; Electronic journals; Periodicals; Periodicals; 363.8
• DOI: 10.1155/2015/364185
• Languages: English
• ISSNs: 2090-0724

Abstract

Abstract : Cubiu is a vegetable of Solanaceae family, native to the Amazon, which is widely distributed through Brazil, Peru, and Colombia. It is used in food, medicine, and cosmetics by native populations. Research has shown that cubiu extracts have antioxidant activities with great biological relevance. We performed a phytochemical screening to identify the main chemical groups that could confer antioxidant activity to this extract. Several tests and qualitative precipitation specific staining for major classes of secondary metabolites were used. Antioxidant capacity in vitro tests (DPPH and ABTS) were also used to assess the extract's ability to sequester free radicals of 70% hydroethanolic and aqueous extracts of cubiu flour. Alkaloids, organic acids, phenols, flavonoid glycosides, and coumarins were found in the hydroethanolic extract while the aqueous extract presented anthocyanins, gums, tannins and mucilage, amino groups, and volatile and fixed acids. For in vitro tests, the I C 50 value obtained in the DPPH assay was 606.3 ± 3.5 μ g/mL while that for the ABTS assay was 290.3 ± 10.7 µ g/mL. Although cubiu extracts present chemical compounds directly related to antioxidant activity, our results show that it has a low antioxidant activity. Additional studies will be needed to isolate and characterize specific compounds to further assess antioxidant activity.