Full ablative versus fractional ablative laser therapy for Dowling–Degos disease. Issue 4 (3rd October 2018)

• Record Type: Journal Article
• Authors: Seitz, Anna‐Theresa; Sterz, Helen; Strehlow, Vincent; Nagel, Stephanie; Dumann, Konstantin; Grunewald, Sonja; Simon, Jan C.; Kunz, Manfred
• Is Part Of: Lasers in surgery and medicine. Volume 51:Issue 4(2019)
• Page Start: 321
• Page End: 324
• Publication Date: 2018-10-03
• Subjects: Dowling–Degos disease -- Galli–Galli disease -- fractional laser therapy -- full ablative laser therapy -- CO2 laser -- Er:YAG laser -- genetics -- genodermatosis; Lasers in medicine -- Periodicals; Lasers in surgery -- Periodicals; 617
• DOI: 10.1002/lsm.23021
• Languages: English
• ISSNs: 0196-8092

Abstract

Abstract : Dowling–Degos disease (DDD) is a rare autosomal‐dominant genodermatosis with limited treatment possibilities. Although the efficacy of ablative laser therapy has been reported, we sought to examine the efficacy of fractional versus full ablative laser therapy in a female patient with DDD in a split‐side report. We treated the lesions on the right side of the patient's upper abdomen with an ablative fractional CO2 laser and the lesions on the left side of the upper abdomen with a full ablative Er:YAG laser (erbium‐doped yttrium aluminium garnet laser) three times at monthly intervals. After three laser sessions, the lesions treated with the Er:YAG laser showed a complete response, whereas the fractional CO2 laser treatment was less effective. After the three treatments were performed, the right side of the patient's upper abdomen and portions of her lower abdomen and chest were also treated with the Er:YAG laser in full ablation mode with the same settings. After 1 year of follow up, there was no recurrence observed. Lasers Surg. Med. © 2018 Wiley Periodicals, Inc.