Whole-genome characterization of Shewanella algae strain SYT3 isolated from seawater reveals insight into hemolysis. (December 2018)

• Record Type: Journal Article
• Authors: Wu, Zong-Yen; Ho, Shu-Peng; Cheng, Jan-Fang; Tung, Kwong-Chung; Hong, Yu-Kai; Chen, Shi-Yu; Menzer, Alexander; Chen, Ying-Ju; Huang, Yao-Ting; Liu, Po-Yu
• Is Part Of: Future microbiology. Volume 13:Number 16(2018)
• Page Start: 1709
• Page End: 1717
• Publication Date: 2018-12
• Subjects: beta-lactamase OXA-55 -- hemolysin -- hemolytic activity -- Shewanella algae; Microbiology -- Research -- Periodicals; 616.9041
• DOI: 10.2217/fmb-2018-0267
• Languages: English
• ISSNs: 1746-0913

Abstract

Aim: To describe the genomic characteristics of seawater-borne hemolytic Shewanella algae and its resistance genes.Materials & methods: Whole genome sequence of S. algae SYT3 was determined using llumina MiSeq platform. Multiple-database-based analysis was performed to identify the genetic background of its hemolytic activity and the antibiotic resistance genes.Results: S. algae SYT3 possesses a homolog of the hly operon involved in the synthesis of hemolysin. We also identified candidate genes associated with resistance to β-lactam antibiotics ( bla OXA-55 ) and fluoroquinolone ( qnrA3 ).Conclusion: The study provides an insight into the hemolytic activity of S. algae . Our findings also suggested S. algae as a potential reservoir of antimicrobial resistance determinants.