Functional comparison of different jailed balloon techniques in treating non-left main coronary bifurcation lesions. (1st October 2022)

• Record Type: Journal Article
• Authors: Wang, Jingpu; Li, Chenguang; Ding, Daixin; Zhang, Mingyou; Wu, Yizhe; Xu, Rende; Lu, Hao; Chen, Zhangwei; Chang, Shufu; Dai, Yuxiang; Qian, Juying; Zhang, Feng; Tu, Shengxian; Ge, Junbo
• Is Part Of: International journal of cardiology. Volume 364(2022)
• Page Start: 20
• Page End: 26
• Publication Date: 2022-10-01
• Subjects: Non-left main coronary bifurcation -- Active jailed balloon technique -- Conventional jailed balloon technique -- Murray law-based quantitative flow ratio; A-JBT Active Jailed Balloon Technique -- CBL Coronary Bifurcation Lesion -- C-JBT Conventional Jailed Balloon Technique -- MV Main Vessel -- μQFR Murray law-based Quantitative Flow Ratio -- SAQ Seattle Angina Questionnaire -- SB Side Branch; Cardiology -- Periodicals; Electronic journals; 616.12
• DOI: 10.1016/j.ijcard.2022.05.036
• Languages: English
• ISSNs: 0167-5273

Abstract

Abstract: Background: There is a paucity of data comparing functional difference between active jailed balloon technique (A-JBT) and conventional jailed balloon technique (C-JBT) in treating non-left main coronary bifurcation lesions (CBLs). Methods: In this retrospective cohort study, we consecutively enrolled 232 patients with non-left main CBLs who underwent percutaneous coronary intervention (PCI) using JBTs between January 2018 and March 2019. Among them, 191 patients entered the final analysis with 12-months angiographic follow-up. We stratified patients into A-JBT group (130 patients) and C-JBT group (61 patients). The functional analysis by Murray law-based quantitative flow ratio (μQFR) and Seattle angina questionnaire (SAQ) were performed to compare the two techniques. Results: Compared with C-JBT group, A-JBT group observed a lower abrupt (0.8% vs. 11.1%, p = 0.002) and final SB occlusion (0 vs. 7.9%, p = 0.005). Meanwhile, A-JBT group had a significantly higher μQFR of side branch (SB) both post-PCI and 12-months follow-up (median [interquartile range (IQR)]: 0.91 (0.86–0.96) vs. 0.82 (0.69–0.92), p < 0.001; median [IQR]: 0.95 (0.89–0.98) vs. 0.85 (0.74–0.93), p < 0.001) than C-JBT group. Besides, A-JBT group gained a μQFR improvement at follow-up period compared with post-PCI data (median [IQR]: 0.95 [0.89–0.98] vs. 0.91[0.86–0.96] of SB, p < 0.001) and a higher SAQ scores at 12-months follow-up compared with C-JBT group (p < 0.001). Conclusions: Compared with C-JBT, A-JBT provided excellent SB protection during MV stenting and improved the SB functional blood flow as well as the angina relief even after 12 months. Highlights: Active-jailed balloon technique provides a new means for protecting the side branch of coronary bifurcation lesions. Quantitative flow ratio is initially used to evaluate the coronary bifurcation lesions. Active-jailed balloon technique can reduce side branch occlusion as well as improve the functional blood flow.