Genetic association analysis reveals significant effect of β-casein A1/A2 loci on production & reproduction traits in Frieswal crossbred cows. Issue 8 (16th November 2020)

• Record Type: Journal Article
• Authors: Kumar, Adesh; Singh, Ran Vir; Chauhan, Anuj; Ilayakumar, K; Kumar, Sushil; Kumar, Amit; Sonwane, Arvind; Kumar, Subodh; Panigrahi, Manjit; Bhushan, Bharat
• Is Part Of: Biological rhythm research. Volume 51:Issue 8(2020)
• Page Start: 1259
• Page End: 1272
• Publication Date: 2020-11-16
• Subjects: Beta-casein -- A1/A2 -- association -- milk production -- pre-sleep -- crossbred; Biological rhythms -- Periodicals; Chronobiology -- Periodicals; Cycles -- Periodicals; Biological Clocks; Chronobiology; Circadian Rhythm; 570
• DOI: 10.1080/09291016.2019.1571705
• Languages: English
• ISSNs: 0929-1016

Abstract

ABSTRACT: Milk β-casein has attracted extensive research interest in the dairy industry and animal breeding as a source of high-quality protein for human diet; however, adverse health effects have been ascribed to A1 β-casein variant consumption. A study was conducted to genotype the polymorphism in milk β-casein gene and examines the potential association between β-casein genotypes and milk production and reproduction traits in population of Frieswal cows. β-Casein A1/A2 genotype had significant effect (P ≤ 0.05) on several production traits including Total Milk Yield (TMY) (P ≤ 0.05), Milk Milk yield 300 days (MY300) (P ≤ 0.05), Lactation Length (LL) (P ≤ 0.01) and Peak Yield (PY) (P ≤ 0.01). β-Casein A1A1 genotype cows had significantly lower TMY, MY300, PY and DP as compared to A1A2 and A2A2 genotypes. A1A2 genotype had highest TMY, MY300, PY and DP; however, A2A2 and A1A2 genotypes were not significantly different from each other. The results pointed towards the superiority of A2 β-casein variant for several production traits in crossbreds. Further, with higher price of A2 milk, the inclusion of β-casein A1/A2 genotype in the selection of crossbreds offers higher profitability from dairy enterprise as well as provides a nutritional wellness product for consumers.