Camphor sulfonic acid catalyzed a simple, facile, and general method for the synthesis of 2-arylbenzothiazoles, 2-arylbenzimidazoles, and 3H-spiro[benzo[d]thiazole-2, 3′-indolin]-2′-ones at room temperature. Issue 7 (3rd April 2021)

• Record Type: Journal Article
• Authors: Kaur, Gurpreet; Moudgil, Radha; Shamim, Mussarat; Gupta, Vivek Kumar; Banerjee, Bubun
• Is Part Of: Synthetic communications. Volume 51:Issue 7(2021)
• Page Start: 1100
• Page End: 1120
• Publication Date: 2021-04-03
• Subjects: 2-arylbenzimidazoles -- 2-arylbenzothiazoles -- camphor sulfonic acid -- 3H-spiro[benzo[d]thiazole-2, 3′-indolin]-2′-ones -- organocatalysis; Organic compounds -- Synthesis -- Periodicals; Chemistry, Organic; Synthesis; 547.205
• DOI: 10.1080/00397911.2020.1870043
• Languages: English
• ISSNs: 0039-7911

Abstract

Abstract: A simple, mild, eco-friendly, general, and convenient approach has been developed for the synthesis of structurally diverse 2-arylbenzothiazole derivatives from the reactions of 2-aminothiophenol and various aromatic aldehydes using camphor sulfonic acid a low cost, commercially available, efficient organo-catalyst in aqueous ethanol at room temperature. Under the same optimized conditions, a series of 2-arylbenzimidazoles was also synthesized starting from o -phenylenediamines and various aldehydes whereas synthesis of 3 H -spiro[benzo[ d ]thiazole-2, 3′-indolin]-2′-ones was accomplished from the reactions of 2-aminothiophenol and substituted isatins. Graphical Abstract: