Development of Vitreoretinal Lymphoma in a Patient with Sarcoid Uveitis. (18th May 2020)

• Record Type: Journal Article
• Authors: Wartique, Lucie; Jamilloux, Yvan; De Parisot De Bernecourt, Audrey; Kodjikian, Laurent; Ghesquieres, Hervé; Ide, Christophe; Sève, Pascal
• Is Part Of: Ocular immunology and inflammation. Volume 28:Number 4(2020)
• Page Start: 647
• Page End: 650
• Publication Date: 2020-05-18
• Subjects: Primary central nervous system lymphoma -- primary vitreoretinal lymphoma -- sarcoidosis -- uveitis -- vitrectomy; Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.1080/09273948.2019.1605452
• Languages: English
• ISSNs: 0927-3948

Abstract

ABSTRACT: Purpose: The purpose of this article is to report the first case of primary vitreoretinal lymphoma in a patient with sarcoid uveitis. Material and Methods: A 63-year-old woman with biopsy-proven sarcoid uveitis diagnosed 7 years ago was presented for a 6-month history of bilateral intermediate uveitis and gait disturbance with cerebral magnetic resonance imaging suggestive of neurosarcoidosis. Because of corticoids resistance, a vitrectomy and a cerebral biopsy were performed. The final diagnosis was primary central nervous system diffuse lymphoma. Patient died despite the chemotherapy with an initial improvement of visual and neurological features. Conclusion: Ophthalmologists should know that patient followed up with sarcoid uveitis can develop a primary vitreoretinal diffuse large B-cell lymphoma.