Prevalence and associated factors of inter-arm blood pressure difference in Chinese community hypertensive population. Issue 2 (17th February 2021)

• Record Type: Journal Article
• Authors: Yu, Yuling; Liu, Lin; Lo, Kenneth; Tang, Songtao; Feng, Yingqing
• Is Part Of: Postgraduate medicine. Volume 133:Issue 2(2021)
• Page Start: 188
• Page End: 194
• Publication Date: 2021-02-17
• Subjects: Inter-arm blood pressure difference -- hypertension -- prevalence -- associated factor; Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610.5
• DOI: 10.1080/00325481.2020.1826184
• Languages: English
• ISSNs: 0032-5481

Abstract

ABSTRACT: Objectives: This study aimed to investigate the prevalence and associated factors of inter-arm blood pressure difference (IAD) in Chinese community hypertensive population. Methods: The cross-sectional study included 7788 hypertensive patients (3673 male and 4115 female, aged 62.3 ± 13.6 years) in Guangdong, China. IAD was defined as the absolute value of blood pressure (BP) difference between left and right arms. Bilateral BP was measured simultaneously by automated devices. Results: The mean IAD was 4.04 ± 4.33 mm Hg in systolic and 3.19 ± 3.43 mm Hg in diastolic. The prevalence rates of systolic IAD (sIAD)≥5 mm Hg and ≥10 mmHg were 28.9% (n = 2247) and 12.8% (n = 996), respectively. By univariate linear regression, higher sIAD correlated with aging, higher SBP, higher DBP, lower baseline estimated glomerular filtration rate (eGFR), and anti-hypertensive medication (p < 0.05). In multivariate linear regression analysis, higher sIAD was significantly associated with systolic BP (SBP, β = 0.033; 95%CI, 0.025–0.041; p < 0.001), triacylglycerol (β = 0.093; 95%CI, 0.017–0.169; p = 0.016), total cholesterol (β = −0.202; 95%CI, −0.396to −0.009; p = 0.04), and low-density lipoprotein cholesterol (LDL-C; β = 0.304; 95%CI, 0.027–0.582; p = 0.032). Conclusion: The elevated prevalence of large IAD was shown in hypertensive population. Meanwhile, higher levels of SBP, triacylglycerol, total cholesterol, LDL-C, and lower eGFR were associated with higher sIAD.