Benzo[g]coumarin-Based Fluorescent Probes for Bioimaging Applications. (14th June 2018)

• Record Type: Journal Article
• Authors: Jung, Yuna; Jung, Junyang; Huh, Youngbuhm; Kim, Dokyoung
• Other Names: Pino Verónica Academic Editor.
• Is Part Of: Journal of analytical methods in chemistry. Volume 2018(2018)
• Publication Date: 2018-06-14
• Subjects: Chemistry, Analytic -- Periodicals; Chemistry, Analytic -- Technique -- Periodicals; 543.05
• DOI: 10.1155/2018/5249765
• Languages: English
• ISSNs: 2090-8865

Abstract

Abstract : Benzo[g ]coumarins, which consist of coumarins fused with other aromatic units in the linear shape, have recently emerged as an interesting fluorophore in the bioimaging research. The pi-extended skeleton with the presence of electron-donating and electron-withdrawing substituents from the parent coumarins changes the basic photophysical parameters such as absorption and fluorescence emission significantly. Most of the benzo[g ]coumarin analogues show red/far-red fluorescence emission with high two-photon absorbing property that can be applicable for the two-photon microscopy (TPM) imaging. In this review, we summarized the recently developed benzo[g ]coumarin analogues including photophysical properties, synthesis, and applications for molecular probes that can sense biologically important species such as metal ions, cell organs, reactive species, and disease biomarkers.