Exploring the Underlying Genetics of Craniofacial Morphology through Various Sources of Knowledge. (8th December 2016)

• Record Type: Journal Article
• Authors: Roosenboom, Jasmien; Hens, Greet; Mattern, Brooke C.; Shriver, Mark D.; Claes, Peter
• Other Names: ERCAN Ilker Academic Editor.
• Is Part Of: BioMed research international. Volume 2016(2016)
• Publication Date: 2016-12-08
• Subjects: Medicine -- Periodicals; Biology -- Periodicals; Biotechnology -- Periodicals; Life sciences -- Periodicals; 610.5
• DOI: 10.1155/2016/3054578
• Languages: English
• ISSNs: 2314-6133

Abstract

Abstract : The craniofacial complex is the billboard of sorts containing information about sex, health, ancestry, kinship, genes, and environment. A thorough knowledge of the genes underlying craniofacial morphology is fundamental to understanding craniofacial biology and evolution. These genes can also provide an important foundation for practical efforts like predicting faces from DNA and phenotype-based facial diagnostics. In this work, we focus on the various sources of knowledge regarding the genes that affect patterns of craniofacial development. Although tremendous successes recently have been made using these sources in both methodology and biology, many challenges remain. Primary among these are precise phenotyping techniques and efficient modeling methods.