Assessment of Startle Response and Its Prepulse Inhibition Using Posturography: Pilot Study. (22nd May 2016)

• Record Type: Journal Article
• Authors: Polechoński, Jacek; Juras, Grzegorz; Słomka, Kajetan; Błaszczyk, Janusz; Małecki, Andrzej; Nawrocka, Agnieszka
• Other Names: Niznikiewicz Margaret A. Academic Editor.
• Is Part Of: BioMed research international. Volume 2016(2016)
• Publication Date: 2016-05-22
• Subjects: Medicine -- Periodicals; Biology -- Periodicals; Biotechnology -- Periodicals; Life sciences -- Periodicals; 610.5
• DOI: 10.1155/2016/8597185
• Languages: English
• ISSNs: 2314-6133

Abstract

Abstract : Purpose . The aim of this study was to evaluate the possibility of using static posturography in the assessment of sensorimotor gating. Subjects and Methods . Fourteen subjects took part in the experiment. The inhibitory mechanisms of startle reflex were used as the measure of sensorimotor gating. It was evoked by a strong acoustic stimulus (106 dB SPL, 40 ms) which was preceded by the weaker similar signal (80 dB SPL, 20 ms). A stabilographic platform was used to measure sensorimotor gating. Results . Results of static posturography show that the postural sway caused by the reaction to a strong acoustic stimulus is significantly smaller when this stimulus is preceded by the signal of lower intensity (prepulse). Such assessment is only possible in eyes open conditions. Conclusions . Static posturography can be simple and effective method used for diagnosis of sensorimotor gating in humans.