Analysis of the Diagnostic Efficacy of DOTATATE Imaging Combined with CGA and BSP Detection Mode for NEN Patients with Bone Metastasis. (23rd July 2022)

• Record Type: Journal Article
• Authors: Lei, Lei; Du, Tao; Yang, Jianbo; Cai, Liang; Liu, Huipan; Chen, Yue
• Other Names: Teekaraman Yuvaraja Academic Editor.
• Is Part Of: BioMed research international. Volume 2022(2022)
• Publication Date: 2022-07-23
• Subjects: Medicine -- Periodicals; Biology -- Periodicals; Biotechnology -- Periodicals; Life sciences -- Periodicals; 610.5
• DOI: 10.1155/2022/6279826
• Languages: English
• ISSNs: 2314-6133

Abstract

Abstract : In order to explore the clinical efficacy of DOTATATE imaging combined with CGA and BSP in the diagnosis of bone metastasis in patients with NENs, a total of 100 NEN patients treated in our hospital from January 2021 to January 2022 were analyzed. All patients are divided into bone metastasis group and nonmetastasis group according to pathological examination results. The differences of DOTATATE imaging, CGA, and BSP are compared, and ROC curves are obtained to analyze the clinical efficacy of the three indicators in single application and combined diagnosis. The results show that AUC, sensitivity, and specificity of DOTATATE, BSP, and CGA combined diagnosis are higher than those of single diagnosis (P < 0.05 ). It is clearly evident that DOTATATE test, BSP, and CGA can obtain accurate results in the diagnosis of bone metastasis in NEN patients, and those combined diagnosis can improve the diagnostic efficiency.