Overcoming resistance to immunotherapy by teaching old drugs new tricks. (2nd September 2020)
- Record Type:
- Journal Article
- Title:
- Overcoming resistance to immunotherapy by teaching old drugs new tricks. (2nd September 2020)
- Main Title:
- Overcoming resistance to immunotherapy by teaching old drugs new tricks
- Authors:
- Perry, John M.
Li, Linheng - Abstract:
- ABSTRACT: Cancer stem cells (CSCs) underlie resistance to therapy. Cancer develops only in the context of failing immunosurveillance, and stem cells occupy immune privileged microenvironments. Recent evidence demonstrates that CSCs borrow immune privilege from their normal counterparts. However, low doses of doxorubicin can target CSCs by restoring anticancer immunity.
- Is Part Of:
- Molecular & cellular oncology. Volume 7:Number 5(2020)
- Journal:
- Molecular & cellular oncology
- Issue:
- Volume 7:Number 5(2020)
- Issue Display:
- Volume 7, Issue 5 (2020)
- Year:
- 2020
- Volume:
- 7
- Issue:
- 5
- Issue Sort Value:
- 2020-0007-0005-0000
- Page Start:
- Page End:
- Publication Date:
- 2020-09-02
- Subjects:
- Cancer stem cells -- immune escape -- Wnt -- β-catenin -- Akt -- chemoresistance -- immune checkpoints -- immunosurveillance -- immune privilege
Tumors -- Periodicals
Neoplasms
Periodicals
616.99 - Journal URLs:
- http://www.tandfonline.com/loi/kmco20#.VyIIeFL2aic ↗
http://www.tandfonline.com/ ↗ - DOI:
- 10.1080/23723556.2020.1801088 ↗
- Languages:
- English
- ISSNs:
- 2372-3556
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 22820.xml