Intraretinal Cystoid Spaces in Regression of Punctate Inner Choroidopathy Lesions. (17th August 2020)

• Record Type: Journal Article
• Authors: Gan, Yuhong; Zhang, Xiongze; Chen, Ling; Wen, Feng
• Is Part Of: Ocular immunology and inflammation. Volume 28:Number 6(2020)
• Page Start: 938
• Page End: 946
• Publication Date: 2020-08-17
• Subjects: Fluorescein angiography -- intraretinal cystoid spaces -- optical coherence tomography angiography -- punctate inner choroidopathy; Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.1080/09273948.2019.1641210
• Languages: English
• ISSNs: 0927-3948

Abstract

ABSTRACT: Purpose: To describe and evaluate the intraretinal cystoid spaces (ICSs) in the eyes of punctate inner choroidopathy (PIC) patients. Methods: In this observational study, patients diagnosed with PIC were included and reviewed between December 2016 and November 2018. All patients underwent multimodal retinal imaging examinations. Results: Forty-one eyes of 26 patients diagnosed with PIC were included. ICSs were found in 13 eyes (31.7%) of 11 subjects. Statistical analysis revealed that except for spherical equivalent ( P = .020), there were no significant difference between patients with ICSs and those with no ICSs at baseline. There were two types of ICSs according to the multimodal imaging findings. These two types of ICSs appeared with regressive PIC lesion and were stable during the follow-up period. Conclusion: ICSs are commonly observed in PIC and they may be a sign of the restoration stage of the disease rather than a need for further clinical intervention.