A 3D-printed scaffold-based osteosarcoma model allows to investigate tumor phenotypes and pathogenesis in an in vitro bone-mimicking niche. (June 2022)
- Record Type:
- Journal Article
- Title:
- A 3D-printed scaffold-based osteosarcoma model allows to investigate tumor phenotypes and pathogenesis in an in vitro bone-mimicking niche. (June 2022)
- Main Title:
- A 3D-printed scaffold-based osteosarcoma model allows to investigate tumor phenotypes and pathogenesis in an in vitro bone-mimicking niche
- Authors:
- Wang, Mei-Ling
Xu, Nian-Yuan
Tang, Rui-Zhi
Liu, Xi-Qiu - Abstract:
- Graphical abstract: Image 1 Highlights: Similar mechanical and structural properties as cortical bones. Recapitulating osteosarcoma phenotypes in morphology, proliferation, cytoskeleton re-organization and energy expenditure. A remarkable potential of ECM remodeling. The transcriptomic analysis to uncover distinct signaling pathways and molecules. Similar expression patterns of biomarkers as clinical trials.
- Is Part Of:
- Materials today bio. Volume 15(2022)
- Journal:
- Materials today bio
- Issue:
- Volume 15(2022)
- Issue Display:
- Volume 15, Issue 2022 (2022)
- Year:
- 2022
- Volume:
- 15
- Issue:
- 2022
- Issue Sort Value:
- 2022-0015-2022-0000
- Page Start:
- Page End:
- Publication Date:
- 2022-06
- Subjects:
- Materials science -- Periodicals
Biomedical engineering -- Periodicals
Biomedical materials -- Periodicals
620.1 - Journal URLs:
- https://www.sciencedirect.com/journal/materials-today-bio ↗
http://www.sciencedirect.com/ ↗ - DOI:
- 10.1016/j.mtbio.2022.100295 ↗
- Languages:
- English
- ISSNs:
- 2590-0064
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 22791.xml