Control of a microfluidic separation process governed by the Zweifach-Fung effect. Issue 7 (2022)

• Record Type: Journal Article
• Authors: Petit, Nicolas
• Is Part Of: IFAC-PapersOnLine. Volume 55:Issue 7(2022)
• Page Start: 975
• Page End: 980
• Publication Date: 2022
• Subjects: Microfluidics -- device integration technologies -- process control applications -- control of micro- and nano-systems -- control of particulate processes -- delay systems -- non-smooth -- discontinuous optimal control problems; Automatic control -- Periodicals; 629.805
• DOI: 10.1016/j.ifacol.2022.07.571
• Languages: English
• ISSNs: 2405-8963

Abstract

Abstract: This paper presents a microfluidic process of separation of a fluid containing particles. The control input is the ratio of flowrates in the two daughter channels of a bifurcation, which due to the Zweifach-Fung effect, has a direct but nonlinear effect on the particle volume fractions in the channels. The dead-volumes of the device and its capillary tubings cause an input-varying delay of hydraulic type. The paper presents several control problems of practical importance and formulates some concise problem statements for future research along with first simulation results.