Aggressive prolactinomas responsive to temozolomide treatment: Report of two cases. Issue 7 (18th July 2022)

• Record Type: Journal Article
• Authors: Davoudi, Zahra; Hallajnejad, Mohammad; Jamali, Elena; Honarvar, Mohammadjavad
• Is Part Of: Clinical case reports. Volume 10:Issue 7(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-07-18
• Subjects: aggressive prolactinoma -- case report -- pituitary neoplasms -- prolactinoma -- temozolomide; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.6087
• Languages: English
• ISSNs: 2050-0904

Abstract

Abstract: Refractory aggressive prolactinomas are detected after the unresponsiveness to conventional therapies. We report two cases that underwent temozolomide treatment and have been in near‐complete remission ever since. We suggest the pathology techniques for earlier detection and, subsequently, treatment with temozolomide to reduce morbidities and better respond to therapy. Abstract : Patients with refractory aggressive prolactinomas are diagnosed after failure of usual treatments. Since they can have near‐complete remission after treatment with Temozolomide, earlier diagnosis with pathology and treatment can avoid morbidities.