E-133 Evaluation of endovascular catheter push/pull forces and energies within silicone and glass neurovascular models with identical tortuosity. (23rd July 2022)

• Record Type: Journal Article
• Authors: Alyami, M; Berns, H; Lewis, K; Vigil, J; Fennell, B; Ducruet, A; Becker, T
• Is Part Of: Journal of neurointerventional surgery. Volume 14(2022)Supplement 1
• Page Start: A147
• Page End: A148
• Publication Date: 2022-07-23
• Subjects: Nervous system -- Surgery -- Periodicals; Cerebrovascular disease -- Surgery -- Periodicals; 617.48
• DOI: 10.1136/neurintsurg-2022-SNIS.244
• Languages: English
• ISSNs: 1759-8478

Abstract

Abstract : Introduction: This research evaluates force and energy impacts correlated with placement of endovascular catheters into (push) and out (pull) of tortuous neurovascular models of silicone and glass (United Biologics - UB). Three test catheter sizes (Stryker SL-10 1.7F, MicroVention Headway 2.6F, and Medtronic React 68) were placed into the models, using saline (PBS) and UB's SLIP solution, and compared at room (21°C) and body (37°C) temperatures. Materials and Methods: Push and pull forces were measured by the Bioengineering Devices Lab (BDL) at Northern Arizona University (NAU) using a hybrid rheometer (HR2, TA Instruments). A 3D-printed mounting plate held the lure of an 8F guide catheter under the vertical force plate and provided gradual transition to horizontal placement into the vessel models. The models were connected to a flow system, filled with PBS or SLIP solution, and maintained at 21°C or 37°C with a flowrate of 250–300 mL/min. The test catheter lures were affixed to the force plate, fed into the 8F guide catheter, and positioned at the models' first 180° curve. The force plate pushed at 0.25 cm/s for a distance of 8.5 cm, a physiologically-relevant device placement rate, through the 180° curve and the adjacent 360° loop ( Figure 1 -Left ). The rheometer then pulled catheters the same rate and distance, back to the starting position. Three test catheters were placed in both silicone and glass models, using both PBS and SLIP solution, and run at two temperatures (24 tests, 4 repeats, 96 tests total). All tests were subtracted from the baseline force, (test catheter push/pull force in the 8F guide catheter only). Results: Force vs. distance plots were created ( Figure 1 -Right ) and average force and energy graphs (area under the force-distance curves) were compared. Tracking the smaller catheters exhibited large forces when using PBS in silicone and glass. As catheter size increases, the force increases in the silicone model, especially at body temperature, due to softening of the silicone. The reverse was seen in glass models: friction decreased with increased temperature. SLIP solution reduced push force significantly in all tests. Conclusion: The use of UB's SLIP solution decreased push force over 180% in both silicone and glass models at room temperature for the smaller catheters. The larger aspiration catheters had the lowest push force when using SLIP solution in the silicone model at room temperature. Analysis of push energy was consistent with the force data, within 5% error. Disclosures: M. Alyami: 5; C; Aneuvas Technologies, Inc. H. Berns: 5; C; Northern Arizona University. K. Lewis: 5; C; Northern Arizona University. J. Vigil: 5; C; Northern Arizona University. B. Fennell: 5; C; Northern Arizona University. A. Ducruet: 2; C; Medtronic, Stryker, Penumbra, Oculus, Koswire, Cerenovus.. 4; C; Aneuvas Technologies, Inc.. 5; C; Barrow Neurological Institute. T. Becker: 4; C; Aneuvas Technologies, Inc.. 5; C; Northern Arizona University. 6; C; United Biologics.