Is race or ethnicity associated with under‐utilization of statins among women in the United States: The study of women's health across the nation. Issue 12 (30th August 2020)

• Record Type: Journal Article
• Authors: Jackson, Elizabeth A.; Ruppert, Kristine; Derby, Carol A.; Lian, Yinjuan; Chae, Claudia U.; Kazlauskaite, Rasa; Neal‐Perry, Genevieve; El Khoudary, Samar R.; Harlow, Siobán D.; Solomon, Daniel H.
• Is Part Of: Clinical cardiology. Volume 43:Issue 12(2020)
• Page Start: 1388
• Page End: 1397
• Publication Date: 2020-08-30
• Subjects: cardiovascular prevention -- race/ethnicity -- statin therapy -- women; Cardiology -- Periodicals; 616.12005
• DOI: 10.1002/clc.23448
• Languages: English
• ISSNs: 0160-9289

Abstract

Abstract: Background: Rates of statin use among minority women are unclear. Hypothesis: We hypothesized that statin use would vary by race/ethnicity with lower rates among minority women compared with Whites. Methods: Data from the study of women's health across the nation, a multiethnic cohort of women collected between 2009 to 2011 were used to examine reported statin use by race/ethnicity and risk profile. Multivariable logistic modeling was performed to estimate the odds ratio (OR) of statin treatment. Results: Of the 2399 women included, 234 had a diagnosis of atherosclerotic disease (ASCVD), 254 were diabetic (without ASCVD), 163 had an LDL ≥190 mg/dL, and 151 had a 10 year ASCVD pooled risk score ≥7.5%. Statins were used by 49.6% of women with CVD; 59.8% of women with diabetes without known ASCVD; 42.3% of women with an LDL ≥190 mg/dL; and 19.9% of women with an ASCVD risk ≥7.5%. Rates of statin use were 43.8% for women with ≥ two prior ASCVD events and 69.4% for women with ≥ one prior ASCVD event plus multiple high‐risk conditions. Among women eligible for statins, Black women had a significantly reduced adjusted odds of being on a statin (OR 0.53, 95% confidence interval [CI] 0.36‐0.78) compared with White women. Conclusions: In this cohort of multiethnic women, rates of statin use among women who would benefit were low, with Black women having lower odds of statin use than White women.