Cover Feature: Guanosine‐based Hydrogel Integrating Photothermal Effect of PDA‐AuNPs through Dynamic Borate Bond for Photothermal Therapy of Cancer (Chem. Asian J. 15/2022). Issue 15 (26th July 2022)

• Record Type: Journal Article
• Authors: Hu, Xiaopei; Lei, Shangxue; Song, Shaojuan; Xia, Xin; Qi, Jiajia; Liu, Jiang; Zhao, Hang
• Is Part Of: Chemistry, an Asian journal. Volume 17:Issue 15(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-07-26
• Subjects: Borate ester bond -- dynamic covalent bond -- guanosine hydrogel -- PDA-AuNPs -- photothermal therapy; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/asia.202200599
• Languages: English
• ISSNs: 1861-4728

Abstract

Abstract : A dual‐functional guanosine‐based hydrogel (GBPA) integrating the photothermal property of PDA‐AuNPs and the self‐assembly ability of G by introducing dynamic borate ester was developed. Both in vitro and in vivo results confirmed that the GBPA hydrogel not only exhibited excellent photothermal toxicity, stability, injectability, andbiocompatibility, but also possessed high photothermal antitumor activity. These results provide a paradigm for the future design of anticancer hydrogels integrating multiple functions. More information can be found in the Research Article by Jiang Liu et al.