Genomic and immune microenvironment profiling in a case of metastatic intrathyroid thymic carcinoma. Issue 7 (18th July 2022)
- Record Type:
- Journal Article
- Title:
- Genomic and immune microenvironment profiling in a case of metastatic intrathyroid thymic carcinoma. Issue 7 (18th July 2022)
- Main Title:
- Genomic and immune microenvironment profiling in a case of metastatic intrathyroid thymic carcinoma
- Authors:
- Ishii, Hiroki
Tsujikawa, Takahiro
Oishi, Naoki
Kinouchi, Arisa
Sakamoto, Kaname
Mitsuda, Junichi
Ogi, Hiroshi
Itoh, Kyoko
Kondo, Tetsuo
Hirano, Shigeru
Sakurai, Daiju - Abstract:
- Abstract: Metastatic intrathyroid thymic carcinoma (ITTC) is a rare cancer with no effective drugs for controlling. This case report has shown genomic and immune microenvironment profiles in metastatic ITTC and emphasized an immunosuppression via a PD‐1/PD‐L1 pathway, possibly strengthening the rationale for immune checkpoint blockade as a novel treatment.
- Is Part Of:
- Clinical case reports. Volume 10:Issue 7(2022)
- Journal:
- Clinical case reports
- Issue:
- Volume 10:Issue 7(2022)
- Issue Display:
- Volume 10, Issue 7 (2022)
- Year:
- 2022
- Volume:
- 10
- Issue:
- 7
- Issue Sort Value:
- 2022-0010-0007-0000
- Page Start:
- n/a
- Page End:
- n/a
- Publication Date:
- 2022-07-18
- Subjects:
- immune checkpoint inhibitor -- intrathyroid thymic carcinoma -- mutation analysis -- PD‐1/PD‐L1 -- tumor‐immune microenvironment
Medicine -- Periodicals
616.09 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)2050-0904 ↗ - DOI:
- 10.1002/ccr3.6050 ↗
- Languages:
- English
- ISSNs:
- 2050-0904
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 22758.xml