A dual-targeting peptide facilitates targeting anti-inflammation to attenuate atherosclerosis in ApoE−/− mice. Issue 62 (14th July 2022)
- Record Type:
- Journal Article
- Title:
- A dual-targeting peptide facilitates targeting anti-inflammation to attenuate atherosclerosis in ApoE−/− mice. Issue 62 (14th July 2022)
- Main Title:
- A dual-targeting peptide facilitates targeting anti-inflammation to attenuate atherosclerosis in ApoE−/− mice
- Authors:
- Wu, Bo
Zhong, Yuanzhi
Chen, Jinmin
Pan, Xianmei
Fan, Xianglin
Chen, Peier
Fu, Chenxing
Ou, Caiwen
Chen, Minsheng - Abstract:
- Abstract : A dual-targeting peptide towards inflamed endothelial cells is reported, which improves the antiatherogenic effect of anti-inflammatory drug puerarin. Abstract : We report a peptidic dual-targeting drug delivery platform (integrins targeting and self-assembly instructed by matrix metalloproteinases) towards inflamed endothelial cells, which improved the anti-inflammatory ability of the loaded drug ( i.e., puerarin) in vitro and thus improved the antiatherogenic effect of the loaded drug ( i.e., puerarin) in vivo .
- Is Part Of:
- Chemical communications. Volume 58:Issue 62(2022)
- Journal:
- Chemical communications
- Issue:
- Volume 58:Issue 62(2022)
- Issue Display:
- Volume 58, Issue 62 (2022)
- Year:
- 2022
- Volume:
- 58
- Issue:
- 62
- Issue Sort Value:
- 2022-0058-0062-0000
- Page Start:
- 8690
- Page End:
- 8693
- Publication Date:
- 2022-07-14
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/d2cc01457b ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 22769.xml